Evaluation of doxorubicin in three-dimensional culture of breast cancer cells and the response in PI3K/AKT/PTEN signaling pathways: a pilot study
| Autor: | Marina Guimarães Gobbo, Gláucia Maria de Mendonça Fernandes, Rafael Fernandes-Ferreira, Lennon Pereira Caires, Heloisa Cristina Caldas, Débora Aparecida Pires de Campos Zuccari, Newton Antonio Bordin-Junior, Giovana Aparecida Gonçalves Vidotti, Doroteia Rossi Silva Souza |
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| Rok vydání: | 2022 |
| Předmět: |
Vascular Endothelial Growth Factor A
Class I Phosphatidylinositol 3-Kinases PTEN Phosphohydrolase Breast Neoplasms Pilot Projects General Medicine Molecular Docking Simulation Phosphatidylinositol 3-Kinases Doxorubicin Spheroids Cellular Tumor Cells Cultured Humans Female Proto-Oncogene Proteins c-akt Signal Transduction |
| Zdroj: | Women & Health. 62:467-475 |
| ISSN: | 1541-0331 0363-0242 |
| DOI: | 10.1080/03630242.2022.2085842 |
| Popis: | Breast cancer (BC) has a high mortality rate, which is attributed to the absence of effective treatment markers. Doxorubicin (DOX) was evaluated by molecular docking |
| Databáze: | OpenAIRE |
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