Erosion protection benefits of stabilized SnF2 dentifrice versus an arginine–sodium monofluorophosphate dentifrice: results from in vitro and in situ clinical studies
| Autor: | Nicola Hellin, Emma L Macdonald, Nicola X West, Matthew L Barker, Sandra L. Eversole, Joon Seong, Tao He |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
In situ
Enamel paint Arginine Dentistry(all) business.industry Dentistry clinical trial 030206 dentistry Sodium monofluorophosphate erosion In vitro toothwear 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry visual_art Sodium fluoride visual_art.visual_art_medium Dentifrice dentifrice 030212 general & internal medicine business General Dentistry Fluoride |
| Zdroj: | West, N, He, T, Macdonald, E, Seong, J, Hellin, N, Barker, M L & Eversole, S L 2017, ' Erosion protection benefits of stabilized SnF2 dentifrice versus an arginine–sodium monofluorophosphate dentifrice : results from in vitro and in situ clinical studies ', Clinical Oral Investigations, vol. 21, no. 2, pp. 533-540 . https://doi.org/10.1007/s00784-016-1905-1 |
| ISSN: | 1436-3771 1432-6981 |
| DOI: | 10.1007/s00784-016-1905-1 |
| Popis: | ObjectivesThe aim of these investigations was to assess the ability of two fluoride dentifrices to protect against the initiation and progression of dental erosion using a predictive in vitro erosion cycling model and a human in situ erosion prevention clinical trial for verification of effectiveness.Materials and methodsA stabilized stannous fluoride (SnF2) dentifrice (0.454 % SnF2 + 0.077 % sodium fluoride [NaF]; total F = 1450 ppm F) [dentifrice A] and a sodium monofluorophosphate [SMFP]/arginine dentifrice (1.1 % SMFP + 1.5 % arginine; total F = 1450 ppm F) [dentifrice B] were tested in a 5-day in vitro erosion cycling model and a 10-day randomized, controlled, double-blind, two-treatment, four-period crossover in situ clinical trial. In each study, human enamel specimens were exposed to repetitive product treatments using a standardized dilution of test products followed by erosive acid challenges in a systematic fashion.ResultsBoth studies demonstrated statistically significant differences between the two products, with dentifrice A providing significantly better enamel protection in each study. In vitro, dentifrice A provided a 75.8 % benefit over dentifrice B (p p ConclusionThese results support the superiority of stabilized SnF2 dentifrices for protecting human teeth against the initiation and progression of dental erosion.Clinical relevanceStabilized SnF2 dentifrices may provide more significant benefits to consumers than conventional fluoride dentifrices. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink