Prevalence and genotypes of Helicobacter pylori in gastric biopsy specimens from patients with gastroduodenal pathologies in the Cukurova region of Turkey
| Autor: | Fatih Köksal, Togrul Nagiyev, Bahri Abayli, Erkan Yula |
|---|---|
| Přispěvatelé: | Çukurova Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Genotype Turkey Virulence Factors Biopsy Spirillaceae Prevalence Biology Polymerase Chain Reaction Gastroenterology Helicobacter Infections Bacterial Proteins Internal medicine medicine Humans CagA Stomach Ulcer Allele Antigens Bacterial Helicobacter pylori Stomach Bacteriology Prognosis biology.organism_classification digestive system diseases medicine.anatomical_structure Duodenal Ulcer Gastritis medicine.symptom |
| Popis: | The effects of Helicobacter pylori genotypes on clinical prognosis in the Cukurova region of Turkey were investigated by PCR. The prevalence of type I strains carrying the s1c allele, unlike in neighboring regions and countries, was found to be significantly higher in patients with gastritis and/or gastric ulcers ( P = 0.001), and that of type I strains carrying the s1a allele was found to be significantly higher in patients with duodenal ulcers ( P < 0.001). The cagA gene was strongly associated with the more virulent vacA genotypes ( P < 0.001). |
| Databáze: | OpenAIRE |
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