Identification of the main pesticide residue mixtures to which the French population is exposed

Autor: S. Pierlot, Camille Béchaux, Vanessa Graillot, Amélie Crépet, J.Ch. Leblanc, J. Tressou, Fanny Héraud
Přispěvatelé: Méthodologies d'Analyse de Risque Alimentaire (MET@RISK), Institut National de la Recherche Agronomique (INRA), ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)
Jazyk: angličtina
Rok vydání: 2013
Předmět:
[SDV.SA]Life Sciences [q-bio]/Agricultural sciences
multiple exposure
Single plant
010501 environmental sciences
01 natural sciences
Biochemistry
Bayesian nonparametrics
Toxicology
Child
General Environmental Science
2. Zero hunger
education.field_of_study
Principal Component Analysis
Dietary exposure
04 agricultural and veterinary sciences
Middle Aged
040401 food science
cumulative risk assessment
trend
Environmental chemistry
Child
Preschool
France
food risk assessment
co exposure clustering
pesticide residue mixture
Adult
Adolescent
Population
chemicals
Biology
Risk Assessment
Statistics
Nonparametric
Crop
Young Adult
0404 agricultural biotechnology
framework
combined effects
Humans
education
0105 earth and related environmental sciences
Aged
Pollutant
Pesticide residue
food
Pesticide Residues
Bayes Theorem
Environmental Exposure
Pesticide
Models
Theoretical
13. Climate action
diet
Zdroj: Environmental Research
Environmental Research, Elsevier, 2013, 126, pp.125-133. ⟨10.1016/j.envres.2013.03.008⟩
ISSN: 0013-9351
1096-0953
DOI: 10.1016/j.envres.2013.03.008⟩
Popis: Owing to the intensive use of pesticides and their potential persistence in the environment, various pesticide residues can be found in the diet. Consumers are therefore exposed to complex pesticide mixtures which may have combined adverse effects on human health. By modelling food exposure to multiple pesticides, this paper aims to determine the main mixtures to which the general population is exposed in France. Dietary exposure of 3337 individuals from the INCA2 French national consumption survey was assessed for 79 pesticide residues, based on results of the 2006 French food monitoring programmes. Individuals were divided into groups with similar patterns of co-exposure using the clustering ability of a Bayesian nonparametric model. In the 5 groups of individuals with the highest exposure, mixtures are formed by pairs of pesticides with correlations above 0.7. Seven mixtures of 2-6 pesticides each were characterised. We identified the commodities that contributed the most to exposure. Pesticide mixtures can either be components of a single plant protection product applied together on the same crop or be from separate products that are consumed together during a meal. Of the 25 pesticides forming the mixtures, two-DDT and Dieldrin are known persistent organic pollutants. The approach developed is generic and can be applied to all types of substances found in the diet in order to characterise the mixtures that should be studied first because of their adverse effects on health. (C) 2013 Elsevier Inc. All rights reserved.
Databáze: OpenAIRE
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