| Autor: |
George A. Calin, Anil K. Sood, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo, Nicholas B. Jennings, Mian M. Shahzad, Koji Matsuo, Behrouz Zand, Chad V. Pecot, Justin Bottsford-Miller, Maria Ines Almeida, Sherry Y. Wu, Milena S. Nicoloso, Xinna Zhang, Simona Rossi, Cristina Ivan, Hee Dong Han, Masayoshi Shimizu, Riccardo Spizzo, Chunhua Lu, Maitri Y. Shah, Eun-Jung Jung, Masato Nishimura |
| Rok vydání: |
2023 |
| DOI: |
10.1158/2159-8290.22529420.v1 |
| Popis: |
Supplementary Figures 1-12 - PDF file 897K, Relative expression of miR-520d-3p (miR-520d) and miR-520d-5p (miR-520d*) in ovarian cancer cell lines (Figure S1), Kaplan-Meier curves representing the percent progression-free survival in patients with ovarian cancer based on miR-520d-3p median expression levels (Figure S2), miR-520d-5p does not target EphA2 (Figure S3), miR-520d-3p and EphA2 expression levels in miR-520d-3p overexpressing stable clones (Figure S4), Effect of miR-520d-3p expression on cell proliferation (Figure S5), miR-520d-3p and EphA2 levels in xenograft models of miR-520d-3p overexpressing HeyA8 and SKOV3ip1 models (Figure S6), Efficiency of EphA2 targeting siRNAs in HeyA8 cells (Figure S7), Combination of miR-520d-3p and siRNA-EphA2 treatment shows enhanced EphA2 inhibition in vitro (Figure S8), Dose-response curve of miR-520d-3p, si-EphA2-1 and combined miR-520d-3p + si-EphA2-1 in SKOV3ip1 and HeyA8 cells (Figure S9), Treatment with anti-miR-520d-3p can restore EphA2 protein levels in a dose-dependent manner in SKOV3ip1 cells (Figure S10), Effect of combined miR-520d-3p+siEphA2-1 treatment on angiogenesis, proliferation and apoptosis in HeyA8 cells (Figure S11), and Differentially expressed coding genes in miR-520d-3p overexpressing stable clones (Figure S12) |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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