Zinc changes in blood and urine during cyclic parenteral nutrition: relationships with amino acid metabolism
| Autor: | X. Leverve, Henri Faure, Alain Favier, C. Boujet, Josiane Arnaud |
|---|---|
| Přispěvatelé: | Département de biologie intégrée, CHU Grenoble-Hôpital Michallon, Bioénergétique fondamentale et appliquée, Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Biochimie Métabolique, Laboratoire de biologie du stress oxydant, Université Joseph Fourier - Grenoble 1 (UJF), Hamant, Sarah |
| Jazyk: | angličtina |
| Rok vydání: | 1994 |
| Předmět: |
Male
Parenteral Nutrition Time Factors MESH: Amino Acids MESH: Cystinuria 030309 nutrition & dietetics Medicine (miscellaneous) Ultrafiltration Urine 030204 cardiovascular system & hematology MESH: Zinc chemistry.chemical_compound 0302 clinical medicine MESH: Aged 80 and over Amino Acids chemistry.chemical_classification Aged 80 and over MESH: Aged 0303 health sciences Nutrition and Dietetics MESH: Middle Aged biology Middle Aged Amino acid Zinc Biochemistry Cystine Female Adult medicine.medical_specialty Adolescent Urinary system Serum albumin MESH: Serum Albumin Excretion 03 medical and health sciences Internal medicine medicine [SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular Biology Humans [SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology Histidine Serum Albumin Aged MESH: Adolescent Cystinuria MESH: Humans business.industry MESH: Time Factors MESH: Adult MESH: Cystine MESH: Male Endocrinology Parenteral nutrition chemistry MESH: Ultrafiltration biology.protein business MESH: Parenteral Nutrition MESH: Female |
| Zdroj: | British Journal of Nutrition British Journal of Nutrition, Cambridge University Press (CUP), 1994, 72 (5), pp.763-73 |
| ISSN: | 0007-1145 1475-2662 |
| Popis: | Serum Zn, ultrafiltrable Zn and amino acids in serum and urine samples of twenty-seven patients receiving cyclic (12 h/24 h) parenteral nutrition were measured. These samples were collected in patients after a 12 h period of parenteral nutrition, and in the evening after 12 h without parenteral nutrition. The same determinations were performed in ten control subjects who followed the same sampling scheme. Total serum ultrafiltrable Zn showed no significant variations in the patients during parenteral nutrition, and was not significantly different in the two groups although the proportion of the Zn present in the ultrafiltrable fraction was elevated. Serum cystine levels were significantly higher (P= 0·05) in the patients than the control subjects, and cystine excretion was also higher in patients (P< 0·05) and increased after parenteral nutrition (56·0 (SE 6·5)v. 147·1 (SE 20·6) m/12 h;P< 0·001). Histidine levels did not vary significantly in serum after parenteral nutrition and were not different in the patients in comparison with the control subjects. Histidine excretion was not different in the two groups but increased significantly during parenteral nutrition (P< 0·05). Serum albumin was significantly depressed in the patients compared with the control subjects (45·3 (SE 1·5)v. 33·9 (SE 1·5) g/l;P< 0·001). These results suggest that cystine infusion and excretion relate to the changes occurring in serum Zn and in urinary Zn excretion. |
| Databáze: | OpenAIRE |
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