Homocysteinemia in psychiatric disorders: association with dementia and depression, but not schizophrenia in female patients
| Autor: | Bruno Pfuhlmann, S. Kamolz, Matthias Schneider, Andreas Reif |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
medicine.medical_specialty Psychosis Neurology Homocysteine Adolescent chemistry.chemical_compound Risk Factors medicine Dementia Humans Risk factor Psychiatry Biological Psychiatry Depression (differential diagnoses) Aged Aged 80 and over Depression Middle Aged medicine.disease Psychiatry and Mental health chemistry Schizophrenia Etiology Female Neurology (clinical) Psychology |
| Zdroj: | Journal of neural transmission (Vienna, Austria : 1996). 110(12) |
| ISSN: | 0300-9564 |
| Popis: | Homocysteinemia has been reported to be a risk factor for dementia, depression and also schizophrenia, the latter in a gender-specific manner. We have determined homocysteine in female inpatients suffering from various psychiatric diseases to further investigate a possible association between homocysteinemia and psychiatric disorders. Homocysteine was not elevated in schizophrenic females (mean, 11.6+/-5.8 micromol/l); in accordance with previous studies, homocysteinemia could be found frequently in dementia of different aetiology (mean, 17.2+/-6.7 micromol/l), but also to a slighter extent in depressive disorders (mean, 12.9+/-3.8 micromol/l), especially in elderly subjects. We thus suggest that homocysteinemia, at least in females, is an unspecific risk factor for organic brain disorders, but not endogenous psychoses. |
| Databáze: | OpenAIRE |
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