Impact of Rh(D) Blood Group System on Graft Function and Survival in Live-Donor Kidney Transplantation: A Single-Institution Experience
| Autor: | Mohamed A. Bakr, Moustafa Amani, Ahmed B. Shehab El-Din, Amr El-Husseini, Yasser Osman, Hussein Sheashaa |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Urinary system Gastroenterology chemistry.chemical_compound Internal medicine Living Donors medicine Humans Single institution Child Kidney transplantation Transplantation Creatinine Kidney Rh-Hr Blood-Group System business.industry Graft Survival Middle Aged medicine.disease Kidney Transplantation Histocompatibility Surgery medicine.anatomical_structure chemistry Child Preschool Female business Rh blood group system |
| Zdroj: | Transplantation. 78:1693-1696 |
| ISSN: | 0041-1337 |
| DOI: | 10.1097/01.tp.0000144328.68806.dc |
| Popis: | One thousand five hundred consecutive live-donor renal transplants were performed in a single institution. Among these patients, 1,372 patients (group I) received Rh-identical allografts and 128 (group II) received Rh-nonidentical allografts. The two groups were homogenous apart from the prevalence of the Rh nonidentity among unrelated donor-recipient pairs. The rate of acute and chronic rejection was comparable in both groups (P = 0.33 for acute rejection and P = 0.66 for chronic rejection). The mean serum creatinine at 5 years was 1.8 +/- 1 mg/dL for group I and 1.7 +/- 0.9 mg/dL for group II (P = 0.5). The 1-, 5-, and 10-year graft survival rates were 94%, 78%, and 54% for group I and 95%, 82%, and 57% for group II. We found that the Rh(D) blood group system is not likely to be a clinically relevant histocompatibility barrier to live-donor renal transplantation. |
| Databáze: | OpenAIRE |
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