Factors that affect cost and clinical outcome of endovascular aortic repair for abdominal aortic aneurysm

Autor: Hasan H. Dosluoglu, Linda M. Harris, Maciej L. Dryjski, Monica S. O'Brien-Irr, Sonya Noor, G. Richard Curl, Mariel Rivero, Gregory S. Cherr
Rok vydání: 2017
Předmět:
Male
medicine.medical_specialty
Time Factors
Percutaneous
Cost-Benefit Analysis
New York
Kaplan-Meier Estimate
030204 cardiovascular system & hematology
Prosthesis Design
Aortic repair
Disease-Free Survival
Blood Vessel Prosthesis Implantation
03 medical and health sciences
Aortic aneurysm
Postoperative Complications
0302 clinical medicine
Cost Savings
Risk Factors
medicine
Humans
030212 general & internal medicine
Hospital Costs
Aged
Retrospective Studies
Aged
80 and over
Academic Medical Centers
Chi-Square Distribution
business.industry
Endovascular Procedures
Retrospective cohort study
Middle Aged
medicine.disease
Abdominal aortic aneurysm
Blood Vessel Prosthesis
Surgery
Treatment Outcome
Retreatment
Cuff
Female
Cardiology and Cardiovascular Medicine
business
Chi-squared distribution
Aortic Aneurysm
Abdominal
Abdominal surgery
Zdroj: Journal of Vascular Surgery. 65:997-1005
ISSN: 0741-5214
DOI: 10.1016/j.jvs.2016.08.090
Popis: This study evaluated the effect of indication for use (IFU), additional graft components, and percutaneous closure of endovascular aortic repair (PEVAR) on clinical outcomes and cost of endovascular aortic repair (EVAR).Clinical and financial data were obtained for all elective EVARs completed at a university-affiliated medical center between January 2012 and June 2013. Data were analyzed by χThere were 67 elective EVARs. Additional cuffs/extensions were used in 37%, increasing the baseline graft cost by 36% (P .001), total costs by 20% (P .001), and negatively affecting the contribution margin. Aortic neck IFU (P = .02), failure of the index graft to seal the neck (P = .02), and need for an additional cuff (P = .008) were related to the need for reintervention for type Ia endoleak for graft B (Excluder; W. L. Gore and Associates, Flagstaff, Ariz), whereas limb IFU was related to the need for additional limb extension for graft A (Powerlink; Endologix, Irvine, Calif; P .001). Limb extension (P = .06) and failure of the index graft to provide an adequate seal (P .001) were associated with reintervention for type Ib endoleak. Reintervention-free rates at 24 months were 96% for graft A and 94% for graft B (P =.54), but different patterns in reintervention emerged: graft A required reoperation early (2 months) then stabilized; graft B did not require reintervention until 24 months, but rates increased substantially by 25 months. PEVAR was attempted in 61 (91%): 49 (73%) bilaterally, 7 (10%) unilaterally, and 5 (8%) failed. The mean number of closure devices was four (range, 1-9): $1000 (3.5% of total cost). Bilateral PEVAR was associated with shorter operating time than unilateral PEVAR/failed PEVAR (P .001) and lower operating room use costs (P = .005) and total hospital costs (P = .003) than failed PEVAR. The contribution margin was higher for bilateral PEVAR than unilateral PEVAR/failed PEVAR (P = .005). Patients with bilateral PEVAR and unilateral PEVAR were more often discharged on postoperative day 1 than those with failed PEVAR (P = .002). Hospital length of stay (P = .49), operating room duration (P = .31), and total costs (P = .72) were similar for unsuccessful PEVAR and EVAR completed with cutdown.Higher rates of reintervention occurred when EVAR was performed outside of IFU guidelines or when additional components were needed. Additions raised graft costs significantly above baseline. Notable differences in graft performance in complex anatomy and varied patterns of reoperation could be useful in the graft selection process to improve outcome and contain costs. Bilateral PEVAR was associated with lower costs and postoperative day 1 discharge. Attempting PEVAR may be reasonable unless there is serious concern for failure.
Databáze: OpenAIRE
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