Supplementary Figure 7 from DNA-Damage Response during Mitosis Induces Whole-Chromosome Missegregation

Autor: Duane A. Compton, Bassem I. Zaki, John P. Murnane, Lilian Kabeche, Samuel F. Bakhoum
Rok vydání: 2023
DOI: 10.1158/2159-8290.22530480.v1
Popis: Control and irradiated (12 Gy) RPE1 cells stained for Aurora-B (A), p-Hec1 (C), p-Histone H3 (E), and p-Cenp-A (G) in green, and DNA (blue). Centromeres (in red) were stained using anti-centromere antibody (CREST). Insets in A show centromere and Aurora B staining at higher magnifications. Relative fluorescence intensity of p-Hec1 (B), p-Histone H3 (D), and p-Cenp-A (F) compared to centromere staining. Bars represent mean {plus minus} SD, n = 10 cells, >300 kinetochores.
Databáze: OpenAIRE