Macular Pigment Optical Density in a Chinese Sample

Autor:	Dorothy S. P. Fan, Robert F. Lam, Srinivas K. Rao, Dennis S.C. Lam, Fion T. C. Lau
Rok vydání:	2005
Předmět:	Adult Male Aging Adolescent genetic structures Optical density Photometry Cellular and Molecular Neuroscience Asian People Macular Pigment Humans Medicine Chinese subjects Macula Lutea Aged Aged 80 and over Chinese population business.industry Middle Aged Macular degeneration medicine.disease Sensory Systems Ophthalmology Optometry Female sense organs business Retinal Pigments Densitometry
Zdroj:	Current Eye Research. 30:729-735
ISSN:	1460-2202 0271-3683
DOI:	10.1080/02713680590968439
Popis:	Purpose: Extensive efforts have been devoted to determining the macular pigment optical density (MPOD) in Caucasian subjects. Unfortunately, no such data in ethnic groups with naturally dark irises are currently available. In this study, we report the values in a sample of Chinese subjects. Methods: The MPOD was measured psychophysically using a densitometer at 0.25°, 0.50°, 1.00°, and 2.00° eccentricity from the foveal center in 92 Chinese subjects. Results: The spatial profile for the averaged MPOD was approximately exponential in form and showed a decline with age (r = −0.23). Subjects aged below 60 years had significantly higher averaged MPOD than those aged 60 years or above. Significant gender differences, in favor of males, were also found in the middle-age groups. Conclusions: Our study reports for the first time the MPOD in a Chinese population. Baseline information on MPOD would aid future research in preventive measures against age-related macular degeneration.
Databáze:	OpenAIRE
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