Lumbar nerve root compression due to extramedullary hemopoiesis in a patient with thalassemia: complete clinical regression with radiation therapy
| Autor: | Philippos Tsitsopoulos, Dimitris Marinopoulos, Parmenion P. Tsitsopoulos, Dimitris Zevgaridis, Ioannis Anagnostopoulos, Christos Tsonidis |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
medicine.medical_specialty Nerve root medicine.medical_treatment Thalassemia Lesion medicine Humans Intervertebral foramen medicine.diagnostic_test business.industry Nerve Compression Syndromes Lumbosacral Region Dose-Response Relationship Radiation Magnetic resonance imaging General Medicine medicine.disease Magnetic Resonance Imaging Surgery Nerve compression syndrome Radiation therapy Lumbar nerve root compression Treatment Outcome medicine.anatomical_structure Hematopoiesis Extramedullary Female medicine.symptom Spinal Nerve Roots Tomography X-Ray Computed business |
| Zdroj: | Journal of Neurosurgery: Spine. 6:156-160 |
| ISSN: | 1547-5654 |
| DOI: | 10.3171/spi.2007.6.2.156 |
| Popis: | ✓The authors describe the case of a 24-year-old woman who had a history of β-thalassemia and presented with severe symptoms of lumbar nerve root compression due to extramedullary hemopoiesis in the intervertebral foramen. Radiation therapy (2000 cGy in six fractions) was delivered to the mass. The patient’s neurological symptoms completely resolved following treatment. Follow-up images showed a reduction in lesion size. The results of this unique case supported by a review of the literature suggest that radiation therapy alone is an effective modality in the treatment of patients with compression of neural structures due to extramedullary hemopoietic tissue. |
| Databáze: | OpenAIRE |
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