| Autor: |
Ming-Rong Wang, Qi-Min Zhan, Zhi-Hua Liu, Yang Yang, Bo-Shi Wang, Tong-Tong Zhang, Wei Luo, Feng Shi, Jia-Jie Hao, Yu Zhang, Li Shang, Xiao-Min Wang |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1541-7786.22509787 |
| Popis: |
PDF file - 1061K, S Figure 1. Down-regulation of CRT expression reduces PTP1B mRNA and protein expression in KYSE510 cells. S2. PTP1B promotes ESCC cell invasion and migration in KYSE510 cells. KYSE510 cells were transfected with PTP1B-specific siRNA (siRNA PTP1B) or non-targeting siRNA control (siRNA cont). S3. CRT regulates cell motility through PTP1B in ESCC cells. (A-C) 1x105 KYSE150 cells were seeded on 24-well plates with three replicates. S4. Cancer-inflammatory response was minimal in mouse model. S5. CRT regulates PTP1B transcription through Stat5a. S6. The expression of CRT and PTP1B in 176 ESCC tissues was evaluated by immunohistochemistry. S7. Correlation of PTP1B expression with overall survival in patients with CRT high-expressing tumors. S8. Model of CRT-dependent signaling pathway in ESCC cell metastasis. Supplementary Table 1. The candidate genes altered in CRT-siRNA KYSE150 cells as compared with non-targeting siRNA cells detected by cDNA array |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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