Detection of Widespread Metastasis in a Case of Aggressive Carcinoma Showing Thymuslike Differentiation (CASTLE Disease) Using 18F-FDG PET/CT
| Autor: | Ikponmwosa Iyamu, Fangyu Peng, Jason W Wachsmann, John M. Truelson, Dana Mathews |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Multimodal Imaging Metastasis Fluorodeoxyglucose F18 Carcinoma Humans Medicine Radiology Nuclear Medicine and imaging Thyroid Neoplasms Lymph node medicine.diagnostic_test business.industry Thyroidectomy Mediastinum General Medicine medicine.disease Radiation therapy Dissection medicine.anatomical_structure Positron emission tomography Lymphatic Metastasis Positron-Emission Tomography Radiology Radiopharmaceuticals Tomography X-Ray Computed business Nuclear medicine |
| Zdroj: | Clinical Nuclear Medicine. 40:689-691 |
| ISSN: | 0363-9762 |
| DOI: | 10.1097/rlu.0000000000000788 |
| Popis: | A 30-year-old man had a diagnosis of aggressive carcinoma showing thymuslike differentiation (CASTLE disease) and underwent thyroidectomy for tumor resection and bilateral cervical lymph node dissection. Multiple hypermetabolic nodal metastases were detected in the neck and upper mediastinum with fluorine-18-fluoro-2-deoxy-D-glucose-positron emission tomography/computed tomography ((18)F-FDG PET/CT). The patient received radiation therapy and chemotherapy for treatment of metastases. Follow-up (18)F-FDG PET/CT demonstrated resolution of several hypermetabolic lesions previously seen in the neck, but innumerable new hypermetabolic metastatic lesions were visualized. The patient died of this aggressive CASTLE disease despite treatment with surgery, radiation, and systemic chemotherapy. |
| Databáze: | OpenAIRE |
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