Exhaled nitric oxide in preterm infants
| Autor: | K. Lewandowski, T Busch, Ludwig Gortner, KonradJ. Falke, Schaible Tf, Andreas Artlich |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Physiology Nose Nitric Oxide Gastroenterology Nitric oxide Excretion chemistry.chemical_compound Internal medicine Respiration Intubation Intratracheal medicine Humans Spontaneous respiration Expiration Respiratory system Body Weight Infant Newborn Paranasal sinuses medicine.anatomical_structure chemistry Anesthesia Luminescent Measurements Exhaled nitric oxide Infant Premature |
| Zdroj: | Respiration Physiology. 114:195-200 |
| ISSN: | 0034-5687 |
| DOI: | 10.1016/s0034-5687(98)00069-3 |
| Popis: | Nitric oxide (NO) is detectable in the exhaled gas of adults during spontaneous respiration and, according to current knowledge, mainly originates from the paranasal sinuses. We studied total NO excretion rates by chemiluminescence in preterm infants whose paranasal sinuses are known to be only partially pneumatized. NO excretion was 7.15 +/- 1.13 nl/min (mean +/- SD, range 6.33-9.36 nl/min) measured from spontaneously exhaled nasal gas (n = 6) and 0.3 +/- 0.05 nl/min (range 0.26-0.36 nl/min) measured from the lower airways in intubated individuals (n = 3). These values are considerably lower than those reported for older children and adults. Body weight-related amounts of NO excretion, however, seem comparable between infants and adults. |
| Databáze: | OpenAIRE |
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