Preventing antiretroviral anarchy in sub-Saharan Africa
Autor: | O Kaluwa, Felix M Salaniponi, D.S. Nyangulu, N.J. Hargreaves, Anthony D. Harries |
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Rok vydání: | 2001 |
Předmět: |
medicine.medical_specialty
Tuberculosis Sub saharan Anti-HIV Agents Developing country HIV Infections Dosing schedules Acquired immunodeficiency syndrome (AIDS) Antiretroviral Therapy Highly Active medicine Humans Intensive care medicine Africa South of the Sahara Acquired Immunodeficiency Syndrome business.industry Public health Drug Resistance Microbial General Medicine medicine.disease Antiretroviral therapy Communicable Disease Control Immunology Patient Compliance Viral disease business |
Zdroj: | The Lancet. 358:410-414 |
ISSN: | 0140-6736 |
DOI: | 10.1016/s0140-6736(01)05551-9 |
Popis: | Combination antiretroviral therapy has dramatically improved the survival of patients living with HIV and AIDS in industrialised countries of the world. Despite this enormous benefit, there are some major problems and obstacles to be overcome.(1) Treatment of HIV-infection is likely to be lifelong.(2) Unfortunately, many HIV-infected individuals cannot tolerate the toxic effects of the drugs, or have difficulty complying with treatment which involves large numbers of pills and complicated dosing schedules. Poor adherence to treatment leads to the emergence of drug-resistant viral strains that need new combinations of drugs or new drugs altogether. |
Databáze: | OpenAIRE |
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