Repeat protein scaffolds: ordering photo- and electroactive molecules in solution and solid state
| Autor: | Sara H. Mejias, Nazario Martín, Javier López-Andarias, Carmen Atienza, Kevin P. Erazo, Shu Seki, Aitziber L. Cortajarena, Tsuneaki Sakurai, Satoru Yoneda |
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| Rok vydání: | 2016 |
| Předmět: |
Scaffold protein
Materials science Photoconductivity Química orgánica Nanotechnology 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Porphyrin 0104 chemical sciences chemistry.chemical_compound Chemistry Protein structure Template chemistry Molecule Thin film 0210 nano-technology Nanoscopic scale |
| Zdroj: | E-Prints Complutense. Archivo Institucional de la UCM instname Chemical Science E-Prints Complutense: Archivo Institucional de la UCM Universidad Complutense de Madrid Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia |
| Popis: | An innovative approach is investigated in which a protein building block is designed to organize porphyrin molecules. The strategy is based on a modular protein unit with tunable properties including stability, function and self-assembly. The precise control over the organization of photoactive components at the nanoscale is one of the main challenges for the generation of new and sophisticated macroscopically ordered materials with enhanced properties. In this work we present a novel bioinspired approach using protein-based building blocks for the arrangement of photo- and electroactive porphyrin derivatives. We used a designed repeat protein scaffold with demonstrated unique features that allow for the control of their structure, functionality, and assembly. Our designed domains act as exact biomolecular templates to organize porphyrin molecules at the required distance. The hybrid conjugates retain the structure and assembly properties of the protein scaffold and display the spectroscopic features of orderly aggregated porphyrins along the protein structure. Finally, we achieved a solid ordered bio-organic hybrid thin film with anisotropic photoconductivity. |
| Databáze: | OpenAIRE |
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