EVALUATION OF CARDIAC FUNCTION IN SYMPTOMATIC HEART FAILURE PATIENTS IN A SINGLE INFUSION, PHASE 1, DOSE ESCALATION STUDY OF GLIAL GROWTH FACTOR 2

Autor:	Evan L. Brittain, Anthony Caggiano, Andrew Eisen, Daniel J. Lenihan, Douglas B. Sawyer, Sarah Anderson, James A.S. Muldowney, Carrie Geisberg, Lisa A. Mendes
Rok vydání:	2013
Předmět:	Cardiac function curve Ventricular function business.industry medicine.disease Myocardial function Placebo Glial Growth Factor Anesthesia Heart failure Dose escalation medicine Neuregulin Cardiology and Cardiovascular Medicine business
Zdroj:	Journal of the American College of Cardiology. 61:E715
ISSN:	0735-1097
Popis:	Glial Growth Factor 2 (GGF2) is a neuregulin peptide critical for myocardial function. GGF2 improves left ventricular function (LVF) in animal models of cardiac injury. We report echocardiographic findings in a first-in-man, double-blind, placebo controlled, escalating single dose study of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610dfb2437b6210a695806cae0fdc5f8 https://doi.org/10.1016/s0735-1097(13)60715-9 Zobrazit plný text záznamu