Phytohaemagglutinin-Induced Leukocyte Migration Inhibition and Phytohaemagglutinin Skin Test for Screening the Cell-Mediated Immune Response in Children
| Autor: | R. Szigeti, J. Bókay, D. Schuler, T. Reéesz |
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| Rok vydání: | 1980 |
| Předmět: |
Leukocyte migration
Adolescent Immunology Thymus Gland Immune system Immunity Leukocytes medicine Humans Lupus Erythematosus Systemic Immunology and Allergy Phytohemagglutinins Child Phytohaemagglutinin skin test Skin Tests Phytohaemagglutinin Immunity Cellular Lupus erythematosus biology business.industry Immunologic Deficiency Syndromes Infant Newborn Infant Cell Migration Inhibition medicine.disease In vitro Child Preschool biology.protein Down Syndrome business |
| Zdroj: | Allergy. 35:557-562 |
| ISSN: | 1398-9995 0105-4538 |
| DOI: | 10.1111/j.1398-9995.1980.tb01805.x |
| Popis: | Phytohaemagglutinin-induced leukocyte migration inhibition was studied in 72 children and compared with phytohaemagglutinin skin testing. The methods were used for screening the cell-mediated immune response. The in vitro method, which requires only 10-15% of the number of migrating cells as compared with other migration techniques, proved to be more sensitive, but gave some false-positive results when compared with other immunological parameters. Nevertheless, application of the microdroplet leukocyte migration is advantageous, used either simultaneously with the skin test, or as a single screening method in prematures, mature newborns and young infants, where application and/or evaluation of the skin tests is difficult. |
| Databáze: | OpenAIRE |
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