Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss
Autor: | BİJEN KIVÇAK, OSMAN YILMAZ, HATİCE EFSUN KOLATAN, SİNEM ÖZKAYNAK |
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Jazyk: | angličtina |
Rok vydání: | 2011 |
Předmět: | |
Zdroj: | Volume: 35, Issue: 6 757-762 Turkish Journal of Biology |
ISSN: | 1300-0152 1303-6092 |
Popis: | Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-inflammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation. |
Databáze: | OpenAIRE |
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