Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss

Autor: BİJEN KIVÇAK, OSMAN YILMAZ, HATİCE EFSUN KOLATAN, SİNEM ÖZKAYNAK
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Volume: 35, Issue: 6 757-762
Turkish Journal of Biology
ISSN: 1300-0152
1303-6092
Popis: Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-inflammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.
Databáze: OpenAIRE