326 A MULTICENTRE, INTERNATIONAL, DOUBLE BLIND, RANDOMIZED, PLACEBO – CONTROLLED STUDY TO ASSESS THE EFFICACY AND SAFETY OF 2 DIFFERENT REGIMENS OF HYADD4-G IN KNEE OSTEOARTHRITIS

Autor:	K. Pavelka, N. Giordan, F.U. Niethard
Rok vydání:	2010
Předmět:	medicine.medical_specialty business.industry Significant group Placebo-controlled study Biomedical Engineering Osteoarthritis medicine.disease Double blind Rheumatology Weight loss medicine Physical therapy Orthopedics and Sports Medicine medicine.symptom business
Zdroj:	Osteoarthritis and Cartilage. 18
ISSN:	1063-4584
DOI:	10.1016/s1063-4584(10)60353-6
Popis:	were no statistically significant group differences for any of the secondary patient-reported outcomes at week 68. Conclusions: A significant weight reduction improves the knee OA patients’ symptoms, as a high proportion of patients experience an OMERACT-OARSI response at 16 weeks. However, although the sustainability of weight loss was significantly better in the diet group, this trial did not provide any evidence of a difference between continuous attention from a dietician following a 1-year maintenance program compared to either exercise or ‘nothing’ in terms of treating OA symptoms.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ff45c467b99ca7c18be46414602675 Zobrazit plný text záznamu Full Text from ScienceDirect