Occupational Activities: Factors That Tip the Balance From Bone Accrual to Bone Loss

Autor: Steven N. Popoff, Mary F. Barbe
Rok vydání: 2020
Předmět:
Zdroj: Exercise and Sport Sciences Reviews
ISSN: 1538-3008
0091-6331
DOI: 10.1249/jes.0000000000000217
Popis: Bone adaptation to persistent overloading can be counteracted by superimposed inflammatory and loading-induced damage that can tip the balance from bone accrual to loss. Supplemental digital content is available in the text.
It is commonly assumed that beneficial adaptations in bone occur with vigorous exercise, yet any adaptive re/modeling in bone undergoing persistent overloading can be counteracted by superimposed inflammatory, compressive, and tensile loading–induced damage responses above thresholds of tissue fatigue failure and repair. This leads to a tenuous balance between achieving bone accrual and loss.
Databáze: OpenAIRE