Occupational Activities: Factors That Tip the Balance From Bone Accrual to Bone Loss
Autor: | Steven N. Popoff, Mary F. Barbe |
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Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Bone accrual Cumulative Trauma Disorders Perspectives for Progress Physical Exertion Physical Therapy Sports Therapy and Rehabilitation bone Osteocytes Bone and Bones Bone resorption 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation repetitive motion injury Bone Density Osteogenesis medicine Accidents Occupational Animals Humans Orthopedics and Sports Medicine Bone Resorption Occupations Exercise physiology Exercise Adaptor Proteins Signal Transducing Balance (ability) Extramural business.industry fungi anabolism catabolism work related RANK Ligand food and beverages Fatigue testing 030229 sport sciences repetitive overuse injury Models Animal Stress Mechanical business 030217 neurology & neurosurgery |
Zdroj: | Exercise and Sport Sciences Reviews |
ISSN: | 1538-3008 0091-6331 |
DOI: | 10.1249/jes.0000000000000217 |
Popis: | Bone adaptation to persistent overloading can be counteracted by superimposed inflammatory and loading-induced damage that can tip the balance from bone accrual to loss. Supplemental digital content is available in the text. It is commonly assumed that beneficial adaptations in bone occur with vigorous exercise, yet any adaptive re/modeling in bone undergoing persistent overloading can be counteracted by superimposed inflammatory, compressive, and tensile loading–induced damage responses above thresholds of tissue fatigue failure and repair. This leads to a tenuous balance between achieving bone accrual and loss. |
Databáze: | OpenAIRE |
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