Autor: |
Aaron C. Brault, Jay Achar, John D. Klena, Johanna S. Salzer, Jessica A. Belser, Matthew J. Maenner, Joyce Foday, Alhajie Turay, Christin H. Goodman, Laura K. McMullan, César G. Albariño, Jonathan S. Towner, Eric Bergeron, Angela J. Sanchez, Samuel J. Crowe, Alison Jane Basile, Solomon S Kuah, David Q.-H. Wang, Dianna M. Blau, Michel Van Herp, Christopher D. Paddock, Mike Flint, Bobbie R. Erickson, Darren Hertz, Veerle Hermans, Tara K. Sealy, Brandy J. Russell, Scott W. Bearden, Grazia Caleo, Gbessay Saffa, Megan Coffee, Aridth Gibbons, Stuart T. Nichol, Barbara Knust, Brian R. Amman, Shelley Campbell |
Jazyk: |
angličtina |
Rok vydání: |
2016 |
Předmět: |
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Zdroj: |
Emerging Infectious Diseases, Vol 22, Iss 2, Pp 217-223 (2016) Emerging Infectious Diseases |
ISSN: |
1080-6059 1080-6040 |
Popis: |
Odds of survival were greatest when first Ebola virus–positive blood sample collected had low viral load. To determine whether 2 readily available indicators predicted survival among patients with Ebola virus disease in Sierra Leone, we evaluated information for 216 of the 227 patients in Bo District during a 4-month period. The indicators were time from symptom onset to healthcare facility admission and quantitative real-time reverse transcription PCR cycle threshold (Ct), a surrogate for viral load, in first Ebola virus–positive blood sample tested. Of these patients, 151 were alive when detected and had reported healthcare facility admission dates and Ct values available. Time from symptom onset to healthcare facility admission was not associated with survival, but viral load in the first Ebola virus–positive blood sample was inversely associated with survival: 52 (87%) of 60 patients with a Ct of >24 survived and 20 (22%) of 91 with a Ct of |
Databáze: |
OpenAIRE |
Externí odkaz: |
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