Emerging strategies for cancer immunoprevention
| Autor: | Florencia McAllister, Steven D. Leach, Jeffrey C. Roeser |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
STAT3 Transcription Factor
Cancer Research medicine.medical_treatment Cancer immunoprevention Programmed Cell Death 1 Receptor Inflammation Biology medicine.disease_cause Bioinformatics Chemoprevention T-Lymphocytes Regulatory Immune system Monitoring Immunologic Neoplasms Genetics medicine Humans Molecular Biology Cancer prevention Interleukin-6 Interleukin-8 Cancer Immunotherapy Dendritic Cells medicine.disease Interleukin 1 Receptor Antagonist Protein Immunology Th17 Cells medicine.symptom Carcinogenesis |
| Zdroj: | Oncogene. 34(50) |
| ISSN: | 1476-5594 |
| Popis: | The crucial role of the immune system in the formation and progression of tumors has been widely accepted. On one hand, the surveillance role of the immune system plays an important role in endogenous tumor prevention, but on the other hand, in some special circumstances such as in chronic inflammation, the immune system can actually contribute to the formation and progression of tumors. In recent years, there has been an explosion of novel targeted immunotherapies for advanced cancers. In the present manuscript, we explore known and potential various types of cancer prevention strategies and focus on nonvaccine-based cancer preventive strategies targeting the immune system at the early stages of tumorigenesis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink