Seasonal variations in manifestations and activity of systemic lupus erythematosus
| Autor: | S Kiss, M Amit, A J Wysenbeek, Yair Molad |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male medicine.medical_specialty Systemic disease Adolescent Disease Disease activity Rheumatology Immunopathology Internal medicine Lupus Erythematosus Cutaneous medicine Humans Lupus Erythematosus Systemic Pharmacology (medical) skin and connective tissue diseases Aged Aged 80 and over Autoimmune disease Lupus erythematosus business.industry Systemic lupus DNA Middle Aged medicine.disease Connective tissue disease Antibodies Antinuclear Immunology Female Seasons business |
| Zdroj: | Rheumatology. 36:449-452 |
| ISSN: | 1462-0332 1462-0324 |
| DOI: | 10.1093/rheumatology/36.4.449 |
| Popis: | The purpose of the present study was to investigate a possible seasonal pattern in various clinical and laboratory manifestations in a group of systemic lupus erythamatosus (SLE) patients. One hundred and five SLE patients were followed up during a 4 yr period. Data on each of the clinical and laboratory variables examined, as well as the results of the disease activity index (SLEDAI), were plotted against the month during which they were obtained. Photosensitivity was the only variable to show a seasonal pattern, having higher scores during the summer months (1.04 +/- 0.16 in July vs 0.58 +/- 0.12 in December). We were unable to show seasonal patterns in any of the other variables examined. As a group, SLE patients do not show any significant seasonal pattern in disease manifestations and activity, except for photosensitivity. However, such a pattern may exist for the individual patient. |
| Databáze: | OpenAIRE |
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