Atrial myxomas and thrombi: comparison of imaging features on CT

Autor: Hans Scheffel, Thomas Schertler, André Plass, Hatem Alkadhi, Stephan Baumueller, Paul Stolzmann, Sebastian Leschka
Přispěvatelé: University of Zurich, Alkadhi, H
Rok vydání: 2009
Předmět:
Coronary angiography
Adult
Male
medicine.medical_specialty
Contrast Media
610 Medicine & health
Ct attenuation
Statistics
Nonparametric

Diagnosis
Differential

Heart Neoplasms
Coronary thrombosis
medicine
2741 Radiology
Nuclear Medicine and Imaging

Humans
Radiology
Nuclear Medicine and imaging

Fossa ovalis
cardiovascular diseases
Aged
Retrospective Studies
Aged
80 and over

Chi-Square Distribution
business.industry
10042 Clinic for Diagnostic and Interventional Radiology
Coronary Thrombosis
Myxoma
General Medicine
Middle Aged
medicine.disease
Atrial wall
10020 Clinic for Cardiac Surgery
medicine.anatomical_structure
cardiovascular system
Radiographic Image Interpretation
Computer-Assisted

Female
Radiology
Differential diagnosis
Nuclear medicine
business
Tomography
X-Ray Computed

Interatrial septum
Zdroj: AJR. American journal of roentgenology. 192(3)
ISSN: 1546-3141
Popis: OBJECTIVE: The purpose of our study was to compare the imaging features of atrial myxomas and thrombi using CT and to assess the accuracy of CT for determining the origin of myxomas in comparison with surgical findings. MATERIALS AND METHODS: From July 2006 until June 2008, 23 patients (15 women, eight men; mean age, 63 +/- 14 years) with atrial myxomas (n = 13) and thrombi (n = 11) who underwent dual-source CT coronary angiography were included in this retrospective study. Two independent and blinded readers evaluated quantitative (CT attenuation and size) and qualitative (location, origin, shape, mobility, prolapse, and calcifications) parameters at CT. The shape and origin of myxomas were compared with the findings at surgery. RESULTS: No significant differences regarding the CT attenuation of myxomas in comparison with thrombi were found (43 +/- 14 HU vs 57 +/- 30 HU; p = 0.23). Myxomas were significantly larger than thrombi (33 +/- 16 mm vs 21 +/- 7 mm; p < 0.05). The lesions were found equally in the left and right atria (p = 0.11). The origin (p < 0.001), shape (p < 0.05), mobility (p < 0.01), and occurrence of prolapse (p < 0.01) differed significantly between the lesions. Calcifications did not differ between the lesions (p = 0.2). In comparison with surgery, the origin of myxomas was correctly evaluated by CT in 11 of 13 patients (fossa ovalis, n = 5; interatrial septum, n = 4; and lateral atrial wall, n = 2), whereas CT misclassified the origin of two myxomas (posterior and lateral wall left atria at CT vs fossa ovalis at surgery). CONCLUSION: Atrial myxomas and thrombi can be differentiated by their distinguishing features of size, origin, shape, mobility, and prolapse. CT is accurate in determining the origin of myxomas but may fail in some cases.
Databáze: OpenAIRE