Impact of Recommended Maternal Vaccination Programs on the Clinical Presentation of SARS-CoV-2 Infection: A Prospective Observational Study
| Autor: | Maria Luisa, de la Cruz Conty, Maria Begoña, Encinas Pardilla, Marta, Garcia Sanchez, Laura, Gonzalez Rodriguez, Marta Luisa, Muner-Hernando, Ana, Royuela Vicente, Pilar, Pintado Recarte, Alicia, Martinez Varea, Clara, Martinez Diago, Sara, Cruz Melguizo, Oscar, Martinez-Perez, On Behalf Of The Spanish Obstetric Emergency Group |
|---|---|
| Přispěvatelé: | UAM. Departamento de Obstetricia y Ginecología, Institut Català de la Salut, [de la Cruz Conty ML] Fundacion de Investigacion Biomedica, Puerta de Hierro University Hospital of Majadahonda, Madrid, Spain. [Encinas Pardilla MB] Department of Gynecology and Obstetrics, Puerta de Hierro University Hospital of Majadahonda, Madrid, Spain. [Garcia Sanchez M] Department of Gynecology and Obstetrics, Quironsalud Malaga University Hospital, Malaga, Spain. [Gonzalez Rodriguez L] Department of Gynecology and Obstetrics, Alvaro Cunqueiro Hospital of Vigo, Pontevedra, Spain. [Muner-Hernando ML] Department of Gynecology and Obstetrics, La Paz University Hospital, Madrid, Spain. [Royuela Vicente A] IDIPHISA Biomedical Research Institute, Madrid, Spain. [Martinez Diago C] Departament de Ginecologia i Obstetricia, Hospital Universitari de Girona Dr. Josep Trueta, Institut Català de la Salut (ICS), Girona, Spain, Hospital Universitari de Girona Dr Josep Trueta |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Pediatrics viruses Maternal vaccination Embaràs Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproduction::Pregnancy [PHENOMENA AND PROCESSES] lcsh:Medicine Cross immunity Vacunes 0302 clinical medicine fenómenos fisiológicos reproductivos y urinarios::fenómenos fisiológicos de la reproducción::reproducción::embarazo [FENÓMENOS Y PROCESOS] Pregnancy Drug Discovery Pandemic influenza vaccines virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES] Pharmacology (medical) 030212 general & internal medicine Prospective cohort study mezclas complejas::productos biológicos::vacunas [COMPUESTOS QUÍMICOS Y DROGAS] Tetanus virus diseases Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES] Vaccination Infectious Diseases Influenza vaccines Cohort pregnancy maternal immunization diphtheria tetanus pertussis vaccine Presentation (obstetrics) COVID-19 (Malaltia) - Vacunació medicine.drug medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Medicina Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Immunology Article 03 medical and health sciences medicine Pharmacology Complex Mixtures::Biological Products::Vaccines [CHEMICALS AND DRUGS] Diphtheria tetanus pertussis vaccine business.industry SARS-CoV-2 allergology Diphtheria lcsh:R Passive immunization covid 19 Diphtheria-Tetanus-Pertussis Vaccine Covid 19 medicine.disease 030104 developmental biology Maternal immunization Pertussis vaccine Observational study passive immunization business |
| Zdroj: | Vaccines Volume 9 Issue 1 Biblos-e Archivo. Repositorio Institucional de la UAM instname Scientia Vaccines, Vol 9, Iss 31, p 31 (2021) |
| ISSN: | 2076-393X |
| Popis: | The COVID-19 pandemic has raised questions about the possible cross immunity resulting from common vaccination programs and SARS-CoV-2 infection. Therefore, the Spanish Obstetric Emergency group performed a multicenter prospective study on the vaccination status of Influenza and Tdap (diphtheria, tetanus and pertussis vaccine boost administered in adulthood) in consecutive cases of SARS-CoV-2 infection in a pregnancy cohort, in order to assess its possible association with the clinical presentation and severity of symptoms of SARS-CoV-2 infection, as well as to determine the factors that may affect vaccination adherence. A total of 1150 SARS-CoV-2 positive pregnant women from 78 Spanish hospitals were analyzed: 183 had not received either vaccine, 23 had been vaccinated for Influenza only, 529 for Tdap only and 415 received both vaccines. No association was observed between the vaccination status and the clinical presentation of SARS-CoV-2 infection and/or the severity of symptoms. However, a lower adherence to the administration of both vaccines was observed in the Latin-American subgroup. Based on the results above, we reinforce the importance of maternal vaccination programs in the actual pandemic. Health education campaigns should be specially targeted to groups less likely to participate in these programs, as well as for a future SARS-CoV-2 vaccination campaign. This research was supported by public funds obtained in competitive calls: Grant COV20/ 00021 from the Instituto de Salud Carlos III-Spanish Ministry of Health, and co-financed with Fondo Europeo de Desarrollo Regional (FEDER) funds |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|