Impact of coronal and sagittal views on lung gross tumor volume delineation

Autor: Joop C. Duppen, Heidi Lotz, Coen R.N. Rasch, Peter J.C.M. Nowak, Marcel van Herk, Isabelle Fitton, Roel J H M Steenbakkers
Přispěvatelé: Radiotherapy, Biomedical Engineering and Physics, Radiation Oncology, Guided Treatment in Optimal Selected Cancer Patients (GUTS)
Rok vydání: 2016
Předmět:
medicine.medical_treatment
Brachytherapy
General Physics and Astronomy
Atelectasis
Lung/diagnostic imaging
030218 nuclear medicine & medical imaging
0302 clinical medicine
Image Processing
Computer-Assisted
Pericardium
Lung
Target delineation
Manchester Cancer Research Centre
Uncertainty
Mediastinum
General Medicine
CANCER
medicine.anatomical_structure
030220 oncology & carcinogenesis
Calibration
CHEST
Sagittal view
Radiology
Lung cancer
Monte Carlo Method
Algorithms
Coronal view
medicine.medical_specialty
Image Processing
Computer-Assisted/methods
Biophysics
Electrons
CT-PET
03 medical and health sciences
medicine
Humans
Radiology
Nuclear Medicine and imaging
COMPUTED-TOMOGRAPHY
Computer Simulation
Probability
Photons
Radiotherapy
business.industry
ResearchInstitutes_Networks_Beacons/mcrc
Inter-observer variability
Reproducibility of Results
medicine.disease
Sagittal plane
Radiation therapy
Brachytherapy/methods
Coronal plane
NODES
business
Nuclear medicine
OBSERVER VARIATION
Software
Zdroj: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology, 32(9), 1082-1087. Associazione Italiana di Fisica Medica
Physica Medica, 32(9), 1082-1087. Associazione Italiana di Fisica Medica
Fitton, I, Duppen, J C, Steenbakkers, R J H M, Lotz, H, Nowak, P J C M, Rasch, C R N & van Herk, M 2016, ' Impact of coronal and sagittal views on lung gross tumor volume delineation ', Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), vol. 32, no. 9, pp. 1082-7 . https://doi.org/10.1016/j.ejmp.2016.08.005
Physica medica-European journal of medical physics, 32(9), 1082-1087. ELSEVIER SCI LTD
Physica Medica, 32(9), 1082-1087. ELSEVIER SCI LTD
ISSN: 1724-191X
1120-1797
DOI: 10.1016/j.ejmp.2016.08.005
Popis: Background and purpose: To study the impact of coronal and sagittal views (CSV) on the gross tumor volume (GTV) delineation on CT and matched PET/CT scans in non-small cell lung cancer.Material and methods: GTV delineations were performed by 11 experienced radiation oncologists on CT and PET/CT in 22 patients. Two tumor groups were defined: Group I: Primary tumors surrounded by lung or visceral pleura, without venous invasion, and without large extensions to the chest wall or the mediastinum. Group II: Tumors invading the hilar region, heart, large vessels, pericardium, and the mediastinum and/or associated with atelectasis. Tumor volumes and inter-observers variations (SD) were calculated and compared according to the use of axial view only (AW), axial/coronal/sagittal views (ACSW) and ACSW/PET (ACSWP).Results: CSV were not frequently used (57.4% out of 242 delineations on CT). For group I, ACSW didn't improve significantly mean GTVs. SDs were small on CT and on PET (SD = 0.3 cm). For group II, ACSW had 27-46% smaller observer variation (mean SD = 0.7 cm) than AW (mean SD = 1.1 cm). The smaller observer variation of ACSW users was associated with, on average, a 40% smaller delineated volume (p = 0.038). Mean GTV of ACSWP was 21% larger than mean GTV of ACSW on CT.Conclusions: For smaller lung tumors surrounded by healthy lung tissue the effect of multiple axis delineation is limited. However, application of coronal and sagittal windows is highly beneficial for delineation of more complex tumors, with atelectasis and/or pathological lymph nodes even if PET is used. (C) 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
Databáze: OpenAIRE
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