The effect of metabolic and respiratory acidosis on cardiac functions
| Autor: | Sumio Kotani, Terumasa Kagawa, Isamu Miyamoto, Akira Nonoyama, Hiroshige Katsuda |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
medicine.medical_specialty
Physiology Digitalis Contractility chemistry.chemical_compound Dogs Internal medicine medicine Animals Acidosis biology business.industry Sodium Metabolic acidosis Heart Hydrogen-Ion Concentration medicine.disease biology.organism_classification Lactic acid Perfusion Respiratory acidosis chemistry Ventricular fibrillation Ventricular Fibrillation Cardiology Potassium Arterial blood Cardanolides Acidosis Respiratory medicine.symptom Cardiology and Cardiovascular Medicine business Muscle Contraction |
| Zdroj: | Japanese circulation journal. 34(2) |
| ISSN: | 0047-1828 |
| Popis: | Experiment was undertaken to evaluate the effects of acidosis upon the susceptibility of the heart by measuring digitalis tolerance, myocardial contractility, and ventricular fibrillation thresh-old. The significant reductions in acetyl stro-phanthidin tolerance, left ventricular contractile force, and ventricular fibrillation threshold value were found during metabolic acidosis induced by lactic acid infusion, whereas they were maintained at almost control values during respiratory acidosis. Moreover, the decreased myocardial contractility after total body perfusion was relative to the decreased arterial blood pH caused by the metabolic factor. |
| Databáze: | OpenAIRE |
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