Clinical and Laboratory Predictors of Dehydration Severity in Children with Diabetic Ketoacidosis
Autor: | Kimberly S. Quayle, Nicole Glaser, Jennifer L. Trainor, Julie K. McManemy, Arleta Rewers, Aris Garro, T. Charles Casper, Simona Ghetti, Lise E. Nigrovic, Cody S. Olsen, Leah Tzimenatos, Maria Y. Kwok, Kathleen M. Brown, Nathan Kuppermann, Michael J. Stoner, Sage R. Myers, Jeff E. Schunk, Jonathan E. Bennett |
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Rok vydání: | 2021 |
Předmět: |
Pediatric emergency
Resuscitation medicine.medical_specialty endocrine system diseases Diabetic ketoacidosis medicine.diagnostic_test business.industry nutritional and metabolic diseases Physical examination medicine.disease Large cohort law.invention Randomized controlled trial law Secondary analysis Pediatrics Perinatology and Child Health Emergency medicine Medicine business |
Zdroj: | Section on Emergency Medicine Program. |
Popis: | Objectives The degree of dehydration in children with diabetic ketoacidosis (DKA) is challenging to discern on presentation and its association with DKA outcomes is unclear. We aimed to characterize the degree of dehydration at presentation of DKA in a large cohort of children and to identify clinical and biochemical factors associated with severity of dehydration and outcomes. Methods This was a planned secondary analysis of data from the Pediatric Emergency Care Applied Research Network (PECARN) Fluid Therapies Under Investigation in DKA (FLUID) Study, a randomized clinical trial of fluid resuscitation protocols for children with DKA. Admission laboratory and physical examination data from … |
Databáze: | OpenAIRE |
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