Visible‐Light‐Assisted Gold‐Catalyzed Fluoroarylation of Allenoates

Autor:	Chao Feng, Hai‐Jun Tang, Yu‐Feng Zhang, Xinggui Zhang
Rok vydání:	2020
Předmět:	Chemical substance 010405 organic chemistry Aryl Allene chemistry.chemical_element General Chemistry General Medicine 010402 general chemistry Hydrogen fluoride 01 natural sciences Redox Combinatorial chemistry Catalysis 0104 chemical sciences chemistry.chemical_compound chemistry Fluorine Stereoselectivity
Zdroj:	Angewandte Chemie. 132:5280-5285
ISSN:	1521-3757 0044-8249
Popis:	A strategically novel synthetic method for the fluoroarylation of allenic ester was developed that enables the expedient construction of a host of β-fluoroalkyl-containing cinnamate derivatives. The reaction proceeds through visible-light-promoted gold redox catalysis, occurs smoothly under very mild reaction conditions, accommodates a large variety of functional groups, and more importantly allows the incorporation of fluorine and aryl groups with excellent regio- and stereoselectivity. The concomitant activation mode for both the allene motif and the hydrogen fluoride is key for the success of the reaction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c7f94f954880ac5f6bc12fe751cc4a https://doi.org/10.1002/ange.201916471 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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