Liver adenomatosis: serial investigation on MRI
| Autor: | Wirana Angthong, Bong Soo Kim, Paul H. Hayashi, Saowanee Srirattanapong, Richard C. Semelka, Jared Peacock, David A. Gerber, John T. Woosley, Anuruddika Ranatunga |
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| Rok vydání: | 2013 |
| Předmět: |
Adenoma
Adult Gadolinium DTPA Male medicine.medical_specialty Adolescent Urology Remission Spontaneous Contrast Media Gastroenterology Malignant transformation Benign tumor Lesion Meglumine Stable Disease Internal medicine Organometallic Compounds medicine Humans Radiology Nuclear Medicine and imaging Retrospective Studies Radiological and Ultrasound Technology business.industry Liver Neoplasms General Medicine Middle Aged Hepatology Hepatocellular adenoma medicine.disease Magnetic Resonance Imaging Natural history Clinical diagnosis Disease Progression Female Radiology medicine.symptom business |
| Zdroj: | Abdominal Imaging. 39:269-282 |
| ISSN: | 1432-0509 0942-8925 |
| DOI: | 10.1007/s00261-013-0056-y |
| Popis: | To describe the natural history of liver adenomatosis (LA), including complications and changes in lesion size over time. Eighteen patients with clinical diagnosis of LA were included. Clinical and biochemical information were collected. The initial and follow-up MR studies were reviewed retrospectively to determine change in lesion size and imaging features. Seventeen patients were women (94.4%). The mean age of the initial MR study was 37.0 years (18–52 years). The median size of the largest lesion was 6.7 cm (range 3.0–13.5 cm). Intratumoral bleeding was detected on MRI in 9 lesions, in 7 patients (38.8%). The median size for hemorrhagic lesions was 7.6 cm (range 4.1–13.5 cm). During the mean follow-up period of 29.4 (range 4–98) months, 10 patients had stable disease (55.6%), and 8 patients had tumor regression (44.4%). Of 8 patients who were followed without intervention, 3 patients (37.5%) had spontaneous regression. No malignant transformation or lesion progression was occurred. During an over 2-year follow-up period, the majority of lesions of LA appeared to remain stable or showed tumor regression. Spontaneous tumor regression can be observed in approximately 37% of individuals in the age range of 28–53 years. |
| Databáze: | OpenAIRE |
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