| Autor: |
Haojun Zhao, Dandan Sheng, Yehua Cai, Yanlin Tang, Mei Li, Jun Chen, Shiyi Chen, Ping Xu |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Contrast Media & Molecular Imaging. |
| ISSN: |
1555-4309 |
| DOI: |
10.1155/2022/6867743 |
| Popis: |
Objective. To investigate the efficacy of contrast-enhanced ultrasound (CEUS) in quantitatively evaluating angiogenesis during patellar tendon healing in rats. Methods. A total of 40 Sprague–Dawley rats were used in this study. The patellar tendons of 30 rats (60 limbs) that underwent incision and suture were treated as the operation group and monitored after 7, 14, and 28 days. The normal patellar tendons of 10 rats (20 limbs) were treated as the control group and monitored on day 0. The ultrasound examination was used to evaluate the structure and blood perfusion of the patellar tendon. Immunohistochemistry was used to assess angiogenesis, and the biomechanical test was used to verify functional recovery of the patellar tendon. Results. The tendons in the operation group were significantly thickened compared with those in the control group ( p p p > 0.05). It was consistent with the change of the CD31-positive staining areas representing angiogenesis of the injured patellar tendons. The PI was positively correlated with the CD31-positive staining area fraction (R = 0.849, p p p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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