Visceral perception: inflammatory and non-inflammatory mediators
Autor: | Lionel Bueno, J Fioramonti |
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Přispěvatelé: | Neuro-Gastroentérologie et Nutrition (NGN), Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole supérieure d'agriculture de Purpan (ESAP) |
Rok vydání: | 2002 |
Předmět: |
Abdominal pain
prostaglandine douleur abdominale Visceral Afferents [SDV]Life Sciences [q-bio] Central nervous system Sensation Visceral Perception Colonic Diseases Functional Mice 03 medical and health sciences ADHENOSINE TRIPHOSPHATE 0302 clinical medicine récepteur polymodal medicine Animals Humans système nerveux réponse gastrointestinale neuropeptide ComputingMilieux_MISCELLANEOUS Irritable bowel syndrome Neurogenic inflammation business.industry potassium Gastroenterology Nociceptors Visceral pain medicine.disease Rats 3. Good health medicine.anatomical_structure bradykinine Hyperalgesia inflammation médiateur Models Animal Immunology ingestion Nociceptor 030211 gastroenterology & hepatology hypersensibilité viscérale Inflammation Mediators medicine.symptom business 030217 neurology & neurosurgery |
Zdroj: | Gut Gut, BMJ Publishing Group, 2002, 51 (sp1), pp.i19-i23 Gut sp1 (51), i19-i23. (2002) |
ISSN: | 0017-5749 |
DOI: | 10.1136/gut.51.suppl_1.i19 |
Popis: | Visceral hypersensitivity is currently the most widely accepted mechanism responsible for abdominal pain. Inflammatory mediators are known to sensitise primary afferents and to recruit silent nociceptors. Recent evidence suggests that non-inflammatory mediators also have the potential to trigger visceral pain. This sequence of events may constitute part of an alerting system which prompts the central nervous system to correct gastrointestinal responses to ingestion. |
Databáze: | OpenAIRE |
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