Visceral perception: inflammatory and non-inflammatory mediators

Autor: Lionel Bueno, J Fioramonti
Přispěvatelé: Neuro-Gastroentérologie et Nutrition (NGN), Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole supérieure d'agriculture de Purpan (ESAP)
Rok vydání: 2002
Předmět:
Abdominal pain
prostaglandine
douleur abdominale
Visceral Afferents
[SDV]Life Sciences [q-bio]
Central nervous system
Sensation
Visceral Perception
Colonic Diseases
Functional

Mice
03 medical and health sciences
ADHENOSINE TRIPHOSPHATE
0302 clinical medicine
récepteur polymodal
medicine
Animals
Humans
système nerveux
réponse gastrointestinale
neuropeptide
ComputingMilieux_MISCELLANEOUS
Irritable bowel syndrome
Neurogenic inflammation
business.industry
potassium
Gastroenterology
Nociceptors
Visceral pain
medicine.disease
Rats
3. Good health
medicine.anatomical_structure
bradykinine
Hyperalgesia
inflammation
médiateur
Models
Animal

Immunology
ingestion
Nociceptor
030211 gastroenterology & hepatology
hypersensibilité viscérale
Inflammation Mediators
medicine.symptom
business
030217 neurology & neurosurgery
Zdroj: Gut
Gut, BMJ Publishing Group, 2002, 51 (sp1), pp.i19-i23
Gut sp1 (51), i19-i23. (2002)
ISSN: 0017-5749
DOI: 10.1136/gut.51.suppl_1.i19
Popis: Visceral hypersensitivity is currently the most widely accepted mechanism responsible for abdominal pain. Inflammatory mediators are known to sensitise primary afferents and to recruit silent nociceptors. Recent evidence suggests that non-inflammatory mediators also have the potential to trigger visceral pain. This sequence of events may constitute part of an alerting system which prompts the central nervous system to correct gastrointestinal responses to ingestion.
Databáze: OpenAIRE