Low vitamin D intake is associated with increase in cardiovascular risk factors in obese adolescents
| Autor: | M. T. de Mello, Sergio Tufik, Ana R Damaso, D. C. Masquio, Flávia Campos Corgosinho, Raquel Ms Campos, Joana Pereira de Carvalho-Ferreira, L. Tock, Bárbara Dal Molin Netto, Carolina Ackel-D’Elia |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatric Obesity Adolescent Endocrinology Diabetes and Metabolism Population Cardiovascular risk factors Physical exercise Eating Young Adult Endocrinology Risk Factors Internal medicine Vitamin D and neurology Medicine Humans Vitamin D education education.field_of_study business.industry Cell adhesion molecule Vitamin D intake Vitamin D Deficiency Inflammatory biomarkers Combined Modality Therapy Weight Reduction Programs Cardiovascular Diseases Female business Plasminogen activator |
| Zdroj: | Europe PubMed Central |
| ISSN: | 1210-0668 |
| Popis: | OBJECTIVES This study aimed to investigate the effect of vitamin D on cardiovascular risk in obese adolescents. METHODS Thirty (16 females/14 males) post-puberty obese adolescents (15-19 years) were involved and measurements of inflammatory biomarkers, body composition, visceral fat, and vitamin D (serum and intake) were performed. The adolescents were submitted to a long-term interdisciplinary therapy with physical exercise, nutritional, psychological, and clinical interventions. RESULTS Negative correlations between vitamin D intake with plasminogen activator inhibitor-1 (PAI-1) (r=-0.69; p=0.01) and vascular cell adhesion molecule (VCAM-1) (r=-0.82; p=0.001) were found in the population analyzed. Improvement in PAI-1, VCAM-1, body composition, and visceral fat, were observed. CONCLUSIONS We showed that low vitamin D intake is associated with an increase in the cardiovascular risk factors in obese adolescents. |
| Databáze: | OpenAIRE |
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