Supraomohyoid Neck Dissection in the Treatment of Head and Neck Tumors: Survival Results in 212 Cases
| Autor: | Gilson Waksman, José Magrin, Rafael P. de Paula, Raimunda N. Pereira, Margarida E. F. Lopes, Luiz Paulo Kowalski, Gilmar F. E. Santo, Humberto Torloni |
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| Rok vydání: | 1993 |
| Předmět: |
Adult
Male Larynx medicine.medical_specialty Adolescent medicine.medical_treatment Facial Muscles Sensitivity and Specificity Metastasis Neck Muscles medicine Humans Risk factor Child Aged Aged 80 and over Salvage Therapy Proportional hazards model business.industry Mortality rate Standard treatment Cancer Neoplasms Second Primary Neck dissection General Medicine Middle Aged Prognosis medicine.disease Surgery Survival Rate medicine.anatomical_structure Otorhinolaryngology Head and Neck Neoplasms Lymphatic Metastasis Carcinoma Squamous Cell Lymph Node Excision Female Lymph Nodes Neoplasm Recurrence Local business Follow-Up Studies |
| Zdroj: | Archives of Otolaryngology - Head and Neck Surgery. 119:958-963 |
| ISSN: | 0886-4470 |
| DOI: | 10.1001/archotol.1993.01880210046007 |
| Popis: | Elective supraomohyoid neck dissection is considered part of standard treatment of oral and oropharyngeal cancer in most institutions, but its role in the treatment of clinically positive neck cancer remains a subject of controversy. The main object of this study is to report the results of 212 consecutive patients who underwent supraomohyoid neck dissections from 1954 to 1990. Most patients had squamous cell carcinoma of the oral cavity. Eighty-six patients (40.6%) had histologically positive lymph nodes in the surgical specimen (sensitivity, 0.55; specificity, 0.53). At the study closing date there were 58.8% actuarial 10-year overall survival rates. Forty-five patients (21.2%) had 50 tumor recurrences (32 local, 13 regional, five distant), and in 40 patients (18.8%) a second primary tumor was diagnosed. A multivariate regression technique based on Cox's proportional hazards model was used, and age (65 years or younger vs older than 65 years) represented the variable with the highest predictive strength with respect to overall survival (relative risk, 2.3). Tumor site, sex, and histologically proved metastasis were also associated with overall survival rates. The same variables were also related to the risk of recurrence. In conclusion, the death rate is mainly related to the control of the primary site tumor and the occurrence of a second primary tumor rather than to neck recurrences. It confirms that supraomohyoid neck dissection is an adequate elective procedure and possibly sufficient in the treatment of a selected group of patients with lip cancer with positive nodes at level 1. |
| Databáze: | OpenAIRE |
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