Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics
Autor: | Unyeong Go, Francesco Castelli, Merete Storgaard, Eskild Petersen, Marion Koopmans, Davidson H. Hamer, Nicola Petrosillo, Sulien Al Khalili, Lone Simonsen |
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Přispěvatelé: | Virology |
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
Middle East respiratory syndrome coronavirus viruses Population Physical Distancing Pneumonia Viral Disease medicine.disease_cause Severe Acute Respiratory Syndrome Article 03 medical and health sciences Betacoronavirus 0302 clinical medicine Case fatality rate Pandemic Influenza Human Correspondence medicine Humans 030212 general & internal medicine education Epidemics Pandemics Disease burden education.field_of_study business.industry SARS-CoV-2 Mortality rate pandemic Age Factors virus diseases COVID-19 Hygiene medicine.disease Hospitalization Pneumonia 030104 developmental biology Infectious Diseases SARS-CVov-2 epidemiology business Coronavirus Infections SARS-CVov-2 pandemic epidemiology Demography |
Zdroj: | The Lancet. Infectious Diseases The Lancet Infectious Diseases Lancet Infectious Diseases, 20(9), E238-E244. Lancet Publishing Group Petersen, E, Koopmans, M, Go, U, Hamer, D H, Petrosillo, N, Castelli, F, Storgaard, M, Al Khalili, S & Simonsen, L 2020, ' Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics ', The Lancet Infectious Diseases, vol. 20, no. 9, pp. e238-e244 . https://doi.org/10.1016/S1473-3099(20)30484-9 |
ISSN: | 1473-3099 |
Popis: | The objective of this Personal View is to compare transmissibility, hospitalisation, and mortality rates for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with those of other epidemic coronaviruses, such as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), and pandemic influenza viruses. The basic reproductive rate (R0) for SARS-CoV-2 is estimated to be 2·5 (range 1·8–3·6) compared with 2·0–3·0 for SARS-CoV and the 1918 influenza pandemic, 0·9 for MERS-CoV, and 1·5 for the 2009 influenza pandemic. SARS-CoV-2 causes mild or asymptomatic disease in most cases; however, severe to critical illness occurs in a small proportion of infected individuals, with the highest rate seen in people older than 70 years. The measured case fatality rate varies between countries, probably because of differences in testing strategies. Population-based mortality estimates vary widely across Europe, ranging from zero to high. Numbers from the first affected region in Italy, Lombardy, show an all age mortality rate of 154 per 100 000 population. Differences are most likely due to varying demographic structures, among other factors. However, this new virus has a focal dissemination; therefore, some areas have a higher disease burden and are affected more than others for reasons that are still not understood. Nevertheless, early introduction of strict physical distancing and hygiene measures have proven effective in sharply reducing R0 and associated mortality and could in part explain the geographical differences. |
Databáze: | OpenAIRE |
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