The retention indices of 201Tl-SPECT in brain tumors
| Autor: | Hiroshi Tagashira, Takatoshi Senba, Hiroki Kitamura, Masashi Hieda, Hiroyuki Shinbata, Kyo Yamashita, Kenichi Kashihara, Hideki Otsuka |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Adolescent 201tl spect Brain tumor Uptake ratio Diagnosis Differential Predictive Value of Tests Glioma medicine Humans Radiology Nuclear Medicine and imaging Thallium Child Aged Aged 80 and over Tomography Emission-Computed Single-Photon medicine.diagnostic_test business.industry Brain Neoplasms Magnetic resonance imaging General Medicine Middle Aged Primary lesion medicine.disease Magnetic Resonance Imaging Predictive value of tests Female Differential diagnosis Radiopharmaceuticals business |
| Zdroj: | Annals of nuclear medicine. 16(7) |
| ISSN: | 0914-7187 |
| Popis: | Objective: The aim of this study was to assess the utility of201Tl SPECT in the differential diagnosis of intracranial tumors and to determine the relationship between201Tl uptake and histological types.Methods: Thirty-eight patients (19 males and 19 females) with thirty-eight brain tumors were evaluated with201Tl-SPECT. The early and delayed201Tl uptake ratio was calculated, and the retention index (RI) was applied as follows; RI=delayed uptake ratio/early uptake ratio.Results: The RI of malignant tumors was higher (0.72±0.18) than that of benign tumors (0.50±0.16) and the difference was statistically significant (p=0.00045). The difference between high-grade glioma (0.80±0.15) and metastatic tumors (0.64±0.19) was statistically significant (p=0.039).Conclusion: 201Tl-SPECT may add useful biochemical information and could differentiate malignant brain tumors from benign lesions, but the RI of metastatic tumors varied depending on the organs with the primary lesion and histological types. |
| Databáze: | OpenAIRE |
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