Effectiveness of 3D T2-Weighted FLAIR FSE Sequences with Fat Suppression for Detection of Brain MR Imaging Signal Changes in Children
| Autor: | Emanuele Bartolini, D. Difeo, Stefano Diciotti, Andrea Bianchi, C. Defilippi, Mario Mascalchi, Pietro Gulino, M. Basile, M. R. Trifan |
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| Přispěvatelé: | Mascalchi, M, Bianchi, A., Basile, M., Gulino, P., Trifan, M.R., Difeo, D., Bartolini, E., Defilippi, C., Diciotti, S. |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Radiology Nuclear Medicine and Imaging Fat suppression Neuroimaging Fluid-attenuated inversion recovery Signal-To-Noise Ratio computer.software_genre Pediatrics 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Imaging Three-Dimensional Voxel medicine Humans Child business.industry Brain Middle Aged Mr imaging Magnetic Resonance Imaging Sagittal plane Hyperintensity medicine.anatomical_structure Coronal plane Female Radiology Neurology (clinical) T2 weighted Nuclear medicine business computer 030217 neurology & neurosurgery |
| Zdroj: | AJNR Am J Neuroradiol Europe PubMed Central |
| Popis: | BACKGROUND AND PURPOSE: T2-weighted FLAIR can be combined with 3D-FSE sequences with isotropic voxels, yielding higher signal-to-noise ratio than 2D-FLAIR. Our aim was to explore whether a T2-weighted FLAIR–volume isotropic turbo spin-echo acquisition sequence (FLAIR-VISTA) with fat suppression shows areas of abnormal brain T2 hyperintensities with better conspicuity in children than a single 2D-FLAIR sequence. MATERIALS AND METHODS: One week after a joint training session with 20 3T MR imaging examinations (8 under sedation), 3 radiologists independently evaluated the presence and conspicuity of abnormal areas of T2 hyperintensities of the brain in FLAIR-VISTA with fat suppression (sagittal source and axial and coronal reformatted images) and in axial 2D-FLAIR without fat suppression in a test set of 100 3T MR imaging examinations (34 under sedation) of patients 2–18 years of age performed for several clinical indications. Their agreement was measured with weighted κ statistics. RESULTS: Agreement was “substantial” (mean, 0.61 for 3 observers; range, 0.49–0.69 for observer pairs) for the presence of abnormal T2 hyperintensities and “fair” (mean, 0.29; range, 0.23–0.38) for the comparative evaluation of lesion conspicuity. In 21 of 23 examinations in which the 3 radiologists agreed on the presence of abnormal T2 hyperintensities, FLAIR-VISTA with fat suppression images were judged to show hyperintensities with better conspicuity than 2D-FLAIR. In 2 cases, conspicuity was equal, and in no case was conspicuity better in 2D-FLAIR. CONCLUSIONS: FLAIR-VISTA with fat suppression can replace the 2D-FLAIR sequence in brain MR imaging protocols for children. |
| Databáze: | OpenAIRE |
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