Epidemic Shigella dysenteriae type 1 in Burundi: panresistance and implications for prevention
Autor: | Stanislas Nyandwi, Robert V. Tauxe, Cecile B. Ivey, Katherine D. Greene, Danielle OlivoIa, Fred C. Tenover, Joy G. Wells, Marcelline Ntakibirora, Patricia M. Griffin, Mathilde Ntibakivayo, S P Wahlquist, Allen A. Ries |
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Rok vydání: | 1994 |
Předmět: |
Adult
Male Shigellosis Shigella dysenteriae Adolescent Burundi Drug resistance medicine.disease_cause Microbiology Disease Outbreaks Ampicillin medicine Immunology and Allergy Humans Shigella Child Antibacterial agent Aged Dysentery Bacillary Aged 80 and over biology Dysentery Infant Drug Resistance Microbial Middle Aged biology.organism_classification medicine.disease Virology Infectious Diseases Case-Control Studies Child Preschool Bloody diarrhea Female Seasons medicine.drug |
Zdroj: | The Journal of infectious diseases. 169(5) |
ISSN: | 0022-1899 |
Popis: | An epidemic of Shigella dysenteriae type 1 infections has affected Africa since 1979. Reported dysentery cases increase sharply in Burundi during September through December. Of stool samples from 189 patients reporting bloody diarrhea in November 1990, a pathogen was identified in 123 (65%). The pathogen was S. dysenteriae type 1 in 82 (67%). All S. dysenteriae type 1 isolates were resistant to ampicillin, chloramphenicol, nalidixic acid, streptomycin, sulfisoxazole, tetracycline, and trimethoprim-sulfamethoxazole. Thirty-two specimens (26%) yielded other Shigella species. Patients with S. dysenteriae type 1 were more likely than those with other Shigella infections to have abdominal pain, "lots of blood" in the stool, blood in the stool specimen examined by the interviewer, recent contact with a person with dysentery, or recent antimicrobial treatment. Thus, the seasonal increase in dysentery was due largely to multidrug-resistant S. dysenteriae type 1, clinical and epidemiologic features may predict such infection, and efforts to control this epidemic must focus on preventing transmission. |
Databáze: | OpenAIRE |
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