Transposable gentamicin resistance in IncW plasmids from Hammersmith Hospital
| Autor: | Naomi Datta, Marilyn E. Nugent |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Transposable element
R Factors EcoRI Microbiology Gentamicin resistance Plasmid medicine Escherichia coli Gene Genetics biology R Plasmids Drug Resistance Microbial DNA biochemical phenomena metabolism and nutrition bacterial infections and mycoses Molecular Weight Acetyltransferase Conjugation Genetic biology.protein DNA Transposable Elements bacteria Gentamicin Gentamicins medicine.drug |
| Zdroj: | Journal of general microbiology. 121(1) |
| ISSN: | 0022-1287 |
| Popis: | A transposon, Tn733, encoding the gentamicin acetyltransferase AAC(3) was found on two gentamicin R plasmids of IncW at Hammersmith Hospital. Transposon Tn733 has a molecular mass of 5.8 megadaltons and gives a characteristic 2.4 megadalton fragment on digestion with EcoRI. The appearance of gentamicin resistance on a transposon will increase the chances of spread of this gene. |
| Databáze: | OpenAIRE |
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