Leprosy: a ‘common’ and curable cause of peripheral neuropathy with skin lesions
| Autor: | David P. Breen, Vaidya S, Deeb J, Radunovic A, Lockwood Dn |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Pathology Biopsy Disease Education Mononeuropathy Leprosy Epidemiology medicine Humans Peripheral Nerves Mycobacterium leprae Ulnar Nerve Aged Skin Travel medicine.diagnostic_test biology Electromyography business.industry Mononeuritis Multiplex Peripheral Nervous System Diseases General Medicine medicine.disease biology.organism_classification Peripheral neuropathy Skin biopsy business |
| Zdroj: | The Journal of the Royal College of Physicians of Edinburgh. 45:38-42 |
| ISSN: | 2042-8189 1478-2715 |
| DOI: | 10.4997/jrcpe.2015.109 |
| Popis: | Leprosy (or Hansen's disease) is a curable chronic infectious disease caused by the acid-fast bacillus Mycobacterium leprae. While leprosy remains one of the most common causes of neuropathy worldwide, its rarity in the UK means that many doctors are unfamiliar with the typical clinical features. This is problematic because early recognition and treatment is vital in order to minimise disease-related complications such as nerve injury. We describe a 75-year-old man who presented with multiple mononeuropathy (mononeuritis multiplex, particularly affecting the ulnar nerves) and typical granulomatous skin lesions, in whom the diagnosis was made on the basis of skin biopsy. We highlight the clinical features, investigations and treatment of the patient, and provide information about the epidemiology and pathogenesis of leprosy. |
| Databáze: | OpenAIRE |
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