Identification of a second messenger of crustacean hyperglycemic hormone signaling pathway in the kuruma prawn Marsupenaeus japonicus

Autor:	Shinji Nagata, Chiaki Nagai, Hideaki Asazuma, Hiromichi Nagasawa
Rok vydání:	2009
Předmět:	medicine.medical_specialty Eyestalk ablation Invertebrate Hormones Marsupenaeus Nerve Tissue Proteins Biology Second Messenger Systems General Biochemistry Genetics and Molecular Biology Arthropod Proteins Cyclic nucleotide chemistry.chemical_compound History and Philosophy of Science Penaeidae Internal medicine medicine Cyclic AMP Animals Cyclic GMP Pancreas General Neuroscience fungi biology.organism_classification Endocrinology chemistry Liver Second messenger system Prawn Hepatopancreas Intracellular Hormone Signal Transduction
Zdroj:	Annals of the New York Academy of Sciences. 1163
ISSN:	1749-6632
Popis:	To address the signaling pathway of crustacean hyperglycemic hormone (CHH) in the kuruma prawn Marsupenaeus japonicus, we measured the intracellular cAMP and cGMP levels in the hepatopancreas, one of the major target tissues of CHH. Removal of CHH-producing cells by bilateral eyestalk ablation decreased intracellular cGMP levels, while little effect on cAMP was observed in the tissue. Similarly, exposure to recombinant CHH significantly increased the cGMP level of the hepatopancreas in vitro, while little change was observed in cAMP. These results suggest that cGMP, rather than cAMP, mediates the CHH signal in hepatopancreas of M. japonicus.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60906474530d6c19c5bbd04b58c0cbe0 https://pubmed.ncbi.nlm.nih.gov/19456392 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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