Mortality risk factors in a Spanish cohort of oldest-old patients hospitalized with COVID-19 in an acute geriatric unit: the OCTA-COVID study
Autor: | Isabel Lozano-Montoya, Francisco J. Gómez-Pavón, Blanca Garmendia-Prieto, Javier Jaramillo-Hidalgo, Pamela Lisette-Carrillo, Maribel Quezada-Feijoo |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Male
medicine.medical_specialty Protective factor Internal medicine Medicine Dementia Humans Mortality Aged Retrospective Studies Polypharmacy Aged 80 and over business.industry SARS-CoV-2 Mortality rate Medical record COVID-19 medicine.disease Hospitalization Risk factors Older adults Cohort Delirium Observational study Female medicine.symptom business Research Paper |
Zdroj: | European Geriatric Medicine |
ISSN: | 1878-7657 1878-7649 |
Popis: | Key summary points Aim The objective of this study is to describe the baseline characteristics of oldest-old patients admitted with COVID-19 to an acute geriatric unit and to determine the factors associated with in-hospital mortality. Findings Dementia, incident delirium, and the CURB-65 score ≥ 3 are independent mortality risk factors. The concurrent use of angiotensin-converting enzyme inhibitors is a protective factor. Message Recognition of geriatric syndromes may be useful to help clinicians establish the prognosis of oldest-old patients admitted to hospital with COVID-19. Purpose To determine predictors of in-hospital mortality related to COVID-19 in oldest-old patients. Design Single-center observational study. Setting and participants Patients ≥ 75 years admitted to an Acute Geriatric Unit with COVID-19. Methods Data from hospital admission were retrieved from the electronic medical records: demographics, geriatric syndromes (delirium, falls, polypharmacy, functional and cognitive status) co-morbidities, previous treatments, clinical, laboratory, and radiographic characteristics. Cox proportional hazard models were used to evaluate in-hospital mortality. Results Three hundred patients were consecutively included (62.7% females, mean age of 86.3 ± 6.6 years). Barthel Index (BI) was |
Databáze: | OpenAIRE |
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