Identification of harman in the rat arcuate nucleus
| Autor: | M. Evans, J.T. Cummins, T.G. Bidder, D.W. Shoemaker, H. G. Boettger |
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| Rok vydání: | 1980 |
| Předmět: |
Male
Pharmacology Medulla Oblongata Chromatography Gas Chromatography Chemistry Pharmacology toxicology Silica column General Medicine Mass spectrometry Fluorescence Rats Harmine chemistry.chemical_compound Alkaloids Spectrometry Fluorescence Mesencephalon Hypothalamus Arcuate nucleus Animals Gas chromatography Caudate Nucleus Diethyl ether Carbolines |
| Zdroj: | NaunynSchmiedeberg's Archives of Pharmacology. 310:227-230 |
| ISSN: | 1432-1912 0028-1298 |
| DOI: | 10.1007/bf00499914 |
| Popis: | This communication describes the presence of 1-methyl-beta-carboline (harman) in the hypophysiotropic area of the hypothalamus which incorporates the arcuate nucleus. Diethyl ether extracts of borate-buffered arcuate homogenates were subjected to silica column chromatography and thin-layer chromatography (TLC). Identification of the beta-carboline was accomplished by use of fluorescent spectrometry, gas chromatography (GC), mass spectrometry (MS) and combined gas chromatography-mass spectrometry (GC-MS). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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