Six-year outcome in subjects diagnosed with attention-deficit/hyperactivity disorder as adults

Autor: Lisa Ekselius, Dan Edvinsson
Rok vydání: 2017
Předmět:
Adult
Male
medicine.medical_specialty
Pediatrics
Clinical cohort
Psykiatri
03 medical and health sciences
Psychiatric comorbidity
0302 clinical medicine
Pharmacotherapy
Quality of life
Surveys and Questionnaires
Outcome Assessment
Health Care
Outpatients
mental disorders
Humans
ADHD
Medicine
Attention deficit hyperactivity disorder
Pharmacology (medical)
Longitudinal Studies
Biological Psychiatry
Outcome
Psychiatry
Psychiatric Status Rating Scales
Original Paper
business.industry
Alcohol and drug
Response
General Medicine
Middle Aged
medicine.disease
Comorbidity
030227 psychiatry
Psychiatry and Mental health
Cross-Sectional Studies
Treatment Outcome
Attention Deficit Disorder with Hyperactivity
Current medication
Methylphenidate
Quality of Life
Physical therapy
Central Nervous System Stimulants
Female
business
030217 neurology & neurosurgery
Zdroj: European Archives of Psychiatry and Clinical Neuroscience
ISSN: 1433-8491
0940-1334
DOI: 10.1007/s00406-017-0850-6
Popis: There are very few studies on the long-term outcome in subjects diagnosed with ADHD as adults. The objective of the present study was to assess this and relate the outcome to whether there was current medication or not and to other potential predictors of favourable outcome. A prospective clinical cohort of adults diagnosed with ADHD according to DSM-IV criteria was followed-up on an average of 6 years after first evaluation (n = 124; mean age 42 years, 51% males). ADHD symptom trajectories were assessed as well as medication, global functioning, disability, health-related quality of life, and alcohol and drug consumption at follow-up. Ninety percent of those diagnosed were initially treated pharmacologically and half of them discontinued treatment. One-third reported remission, defined as not fulfilling any ADHD subtype and a GAF-value last year ≥ 70, which was not affected by comorbidity at baseline. Current medication was not associated with remission. Subjects evaluated and first diagnosed with ADHD as adults are functionally improved at follow-up 6 years later despite a high percentage of psychiatric comorbidity at baseline. Half dropped out of medication, and there was no difference in ADHD remission between subjects with on-going medication at follow-up or subjects without medication, although current medication was related to a higher degree of self-reported global improvement.
Databáze: OpenAIRE
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