Genetic polymorphism of CSN1S2 in South African dairy goat populations
| Autor: | S. Chessa, Carina Visser, Rulien Grobler, E. van Marle-Köster |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Veterinary medicine education.field_of_study Animal breeding Population 0402 animal and dairy science 04 agricultural and veterinary sciences Biology alpha-s2-casein protein content 040201 dairy & animal science 03 medical and health sciences 030104 developmental biology Saanen Polymorphism (computer science) goat milk Casein Genotype Genetic variation genetic variation Animal Science and Zoology alpha-s2-casein genetic variation goat milk protein content Saanen Allele education Inbreeding |
| Zdroj: | South African Journal of Animal Science; Vol 47, No 1 (2017); 72-78 South African Journal of Animal Science, Volume: 47, Issue: 1, Pages: 72-78, Published: 2017 South African journal of animal science 47 (2017): 72–78. doi:10.4314/sajas.v47i1.11 info:cnr-pdr/source/autori:Grobler R.; Visser C.; Chessa S.; van Marle-Koster E./titolo:Genetic polymorphism of CSN1S2 in South African dairy goat populations/doi:10.4314%2Fsajas.v47i1.11/rivista:South African journal of animal science/anno:2017/pagina_da:72/pagina_a:78/intervallo_pagine:72–78/volume:47 |
| ISSN: | 0375-1589 2221-4062 |
| DOI: | 10.4314/sajas.v47i1.11 |
| Popis: | Alpha-s2 casein has a significant influence on protein content in goat milk, and the technological properties important for cheese processing. Specific alleles (A, B, C, E and F) of the alpha (α)s2-casein gene (CSN1S2) result in higher protein, casein and fat content, and improved coagulation properties, which are useful for improved cheese making. The aim of this study was to investigate the polymorphism and genetic variation of CSN1S2 in South African dairy goats, using DNA sequencing technology. Sixty dairy goats (20 Saanes, 20 British Alpine, and 20 Toggenburg) and 20 meat-type goats were sequenced with four primers to distinguish among the seven known alleles for αs2-casein. A total of four alleles (A, B, C and F) for CSN1S2 were observed among the dairy- and meat-type populations with ten genotypes across the populations. The A allele and the AA genotype were the most frequent across the populations, with the favourable AC genotype being the most frequent (0.300) in the Saanen population. Two unique genotypes were detected in the Toggenburg (BB and BF) and one in the meat-type goats (CF). The results indicate moderate genetic variation for αs2-casein in the South African goat populations (42.3–63.6%). Low positive FST values suggest limited inbreeding. This study confirmed the presence of favourable alleles in the South African goat populations, indicating room for genetic improvement using directional selection for favourable genotypes.Keywords: alpha-s2-casein, genetic variation, goat milk, protein content, Saanen |
| Databáze: | OpenAIRE |
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