Syk kinase and Shp2 phosphatase inhibition cooperate to reduce FLT3-ITD-induced STAT5 activation and proliferation of acute myeloid leukemia

Autor:	Briana M. Richine, Ziyue Liu, Reuben Kapur, Elizabeth L. Virts, Baskar Ramdas, Bowling Jd, Raghuveer Singh Mali, Rebecca J. Chan, Boswell Hs, Zhong Yin Zhang, Naoye R
Rok vydání:	2016
Předmět:	0301 basic medicine Cancer Research Myeloid genetic structures Protein Tyrosine Phosphatase Non-Receptor Type 11 Protein tyrosine phosphatase Article 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases medicine STAT5 Transcription Factor Humans Syk Kinase Amino Acid Sequence Enzyme Inhibitors STAT5 Cell Proliferation biology Sequence Homology Amino Acid Cell growth Myeloid leukemia hemic and immune systems Hematology medicine.disease 3. Good health body regions Haematopoiesis Leukemia Leukemia Myeloid Acute 030104 developmental biology medicine.anatomical_structure Oncology fms-Like Tyrosine Kinase 3 030220 oncology & carcinogenesis Fms-Like Tyrosine Kinase 3 biology.protein Cancer research psychological phenomena and processes
Zdroj:	Leukemia
ISSN:	1476-5551
Popis:	Syk kinase and Shp2 phosphatase inhibition cooperate to reduce FLT3-ITD-induced STAT5 activation and proliferation of acute myeloid leukemia
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6075fbbedcde87a88f1dd75ec068f56c https://pubmed.ncbi.nlm.nih.gov/27256702 Zobrazit plný text záznamu Full text from SpringerLink