Bromism caused by mix-formulated analgesic injectables
| Autor: | Yi-Chung Lee, Dong-Zong Hung, Chang Mh, Hsu Cl, Tsan Yt, Hsieh Pf |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
0301 basic medicine medicine.medical_specialty Databases Factual Substance-Related Disorders Health Toxicology and Mutagenesis medicine.medical_treatment Analgesic Toxicology Bromine Compounds Perceptual Disorders 03 medical and health sciences Sodium bromide chemistry.chemical_compound 0302 clinical medicine Hyperchloremia Chlorides Bromide medicine Humans Antipyretic Saline Acid-Base Equilibrium Analgesics Internet 030102 biochemistry & molecular biology business.industry General Medicine Analgesics Non-Narcotic medicine.disease Surgery chemistry 030220 oncology & carcinogenesis Anesthesia Injections Intravenous Histamine H1 Antagonists Female Antihistamine Psychomotor Disorders business Bromism medicine.drug |
| Zdroj: | Human & Experimental Toxicology. 26:971-973 |
| ISSN: | 1477-0903 0960-3271 |
| DOI: | 10.1177/0960327107087797 |
| Popis: | Bromism, chronic bromide intoxication, can be caused by a variety of medicines, but bromism due to pain-relieving injectable medications has not been reported. In this study, the methods used were internet searching on bromide-containing injectables available in Taiwan and the first case report of bromism due to mixed-formulated injectable medication. Many analgesic/antipyretic and antihistamine injections containing bromides are still being used in Taiwan. They contain sodium bromide up to 1000 mg/ampoule or calcium bromide up to 800 mg/amp. A 25-year-old female suffered from forgetfulness and unstable gait after long-term frequent injections of a preparation to relieve head and neck pain. Blood tests showed hyperchloremia (171 mEq/L) and a negative anion gap (−48.7 mEq/L). Serum bromide measured 2150 mg/L. She recovered completely in 3 days with saline treatment. Many bromide-containing injections are still being used in Taiwan. Clinicians should keep alert on this issue to avoid iatrogenic bromism or making misdiagnoses. |
| Databáze: | OpenAIRE |
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