Rotenoid and isoflavone metabolites from an antioxidant seed extract of Dalbergia lanceolaria subsp. paniculata (roxb.) thoth
| Autor: | Ayat A. Mostafa, Usama W. Hawas, Lamia T. Abou El-Kassem, Mohamed S. Abdelfattah |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Antioxidant
Traditional medicine 010405 organic chemistry medicine.medical_treatment Organic Chemistry Plant Science Biology 01 natural sciences Biochemistry Rotenoid 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry chemistry.chemical_compound chemistry medicine Dalbergia lanceolaria |
| Zdroj: | Natural Product Research. 34:613-620 |
| ISSN: | 1478-6427 1478-6419 |
| DOI: | 10.1080/14786419.2018.1491042 |
| Popis: | A new rotenoid named 12-O-methylrotenolol along with five known rotenoid and isoflavone metabolites were isolated from the seeds of Dalbergia lanceolaria subsp. paniculata, collected from Egypt. The structures of these compounds were identified by physical and spectroscopic data measurements ([α]D, UV, 1D- and 2D-NMR and MS). The methanol extract of the seeds exhibited strong antioxidant activity with IC50 value 0.7 µg/µl against DPPH radical, in respect to quercetin as antioxidant reference (IC50 1.5 μM), while the tested compounds from this extract showed weak activities with IC50 values ranged from 19.6 to 33.0 µM. |
| Databáze: | OpenAIRE |
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